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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM70B
All Species:
21.52
Human Site:
Y178
Identified Species:
52.59
UniProt:
Q8WV15
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WV15
NP_872420.1
326
34609
Y178
A
E
P
S
P
A
Y
Y
E
F
I
G
V
S
G
Chimpanzee
Pan troglodytes
XP_001169393
229
24274
Y81
A
E
P
S
P
A
Y
Y
E
F
I
G
V
S
G
Rhesus Macaque
Macaca mulatta
XP_001106413
185
19589
E38
E
S
S
P
A
Y
Y
E
F
I
G
V
R
G
C
Dog
Lupus familis
XP_849617
707
75641
Y359
T
E
H
P
P
A
Y
Y
E
F
V
G
V
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5FW56
369
39343
Y222
T
E
P
S
P
A
Y
Y
E
F
V
G
V
R
S
Rat
Rattus norvegicus
Q7TMP6
351
38598
Y204
V
E
I
T
G
G
Y
Y
E
Y
I
D
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515267
346
37417
Y197
A
E
Q
S
S
S
Y
Y
E
F
V
G
V
S
G
Chicken
Gallus gallus
XP_416937
378
40454
Y230
S
E
Q
S
S
S
Y
Y
E
F
L
G
V
S
S
Frog
Xenopus laevis
Q66IQ1
321
35264
N173
Y
N
C
G
R
I
G
N
S
G
L
Y
Y
E
Y
Zebra Danio
Brachydanio rerio
XP_002665444
321
34691
N174
C
D
L
Y
D
C
A
N
G
G
Y
L
N
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.5
53.3
37.4
N.A.
54.4
50.4
N.A.
67
65
53.9
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
65
53.9
41
N.A.
62
64.3
N.A.
76.5
73.8
67.7
56.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
60
N.A.
73.3
46.6
N.A.
73.3
60
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
66.6
N.A.
80
60
N.A.
86.6
80
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
0
10
40
10
0
0
0
0
0
0
0
0
% A
% Cys:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
0
10
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
10
70
0
0
0
0
0
10
70
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
60
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
10
10
0
10
20
10
60
0
10
30
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
10
30
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
20
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
20
0
0
0
0
10
10
0
% N
% Pro:
0
0
30
20
40
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
10
10
10
% R
% Ser:
10
10
10
50
20
20
0
0
10
0
0
0
0
50
30
% S
% Thr:
20
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
30
10
70
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
10
80
70
0
10
10
10
10
0
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _